Thursday, June 05, 2008

Bee Venom Induces Cancer Cell Death

Bee Venom Induced Cell Cycle Arrest and Apoptosis in Human Cervical Epidermoid Carcinoma Ca Ski Cells
Anticancer Res, 2008 Mar-Apr;28(2A):833-42

Although it has been previously reported that bee venom (BV) can induce apoptosis in many cancer cell lines, there is no information on the effect of BV on human cervical cancer cells and its molecular mechanisms of action are not fully elucidated.

In this study, the possible mechanisms of apoptosis by which BV acts on human cervical cancer Ca Ski cells were investigated…

In conclusion, our data demonstrated that BV-induced apoptosis occurs via a Fas receptor pathway involving mitochondrial-dependent pathways and is closely related to the level of cytoplasmic Ca2+ in Ca Ski cells.

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